刘丽辉简介
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刘丽辉 博士 健康大数据研究中心 实验数据分析主管 中国科学院生物物理所 北京市朝阳区大屯路15号 电子邮件(E-mail) lihui.mm@163.com 电话(Tel) 010-64888544 邮政编码 100101 |
简历 & 研究组工作摘要
主要研究方向：
利用芯片、高通量测序技术系统发掘非编码RNA在肿瘤等各种疾病发生发展以及干细胞分化过程中发挥的重要功能以及发挥功能的机制研究。
2016年至今 中国科学院生物物理研究所，健康大数据研究中心实验平台主管
2009－2016年 中国科学院生物物理研究所，生物信息学理学博士
2005－2009年 河北大学，生物信息学理学学士
代表性论文
1. Lihui Liu#, Haiyan Yue#, Qinghua Liu#, Jiao Yuan#, Jing Li, Guifeng Wei, Xiaomin Chen, Youyong Lu, Mingzhou Guo, Jianjun Luo, Runsheng Chen. LncRNA MT1JP Interacts with TIAR to Modulate the p53 Pathway during Tumorigenesis. Oncotarget. 2015;7: 15787–15800.
2. Tengfei Xiao#, Lihui Liu#, Hongling Li#, Yu Sun#, Huaxia Luo, Tangping Li, Shihua Wang, Stephen Dalton, Robert Chunhua Zhao, Runsheng Chen. Long Noncoding RNA ADINR Regulates Adipogenesis by Transcriptionally Activating C/EBPα. Stem Cell Reports. 2015; 5: 856-865. (Co-first author)
3. Jiahui Chen，Lihui Liu，Guifeng Wei，Wei Wu，Huaxia Luo，JiaoYuan，Jianjun Luo，Runsheng Chen. The long noncoding RNA ASNR regulates， degradation of Bcl-2 mRNA through its interaction with AUF1. Sci Rep-Uk. 2016; 6: 32189
4. Guifeng Wei, Huaxia Luo , Yu Sun, Jiagen Li, Liqing Tian, Wei Liu, Lihui Liu, Jianjun Luo, Jie He, Runsheng Chen. Transcriptome profiling of esophageal squamous cell carcinoma reveals a long noncoding RNA acting as a tumor suppressor. Oncotarget. 2015; 6: 17065-17080.
5. Tengfei Xiao, Yunfei Wang, Huaxia Luo, Lihui Liu, Guifeng Wei, Xiaowei Chen, Yu Sun, Xiaomin Chen, Geir Skogerbø, Runsheng Chen. A differential sequencing-based analysis of the C. elegans noncoding transcriptome. Rna-a Publication of the Rna Society. 2012; 18: 626-639.
6. Jiao Yuan, Haiyan Yue, Meiying Zhang, Jianjun Luo, Lihui Liu, Wei Wu, Tengfei Xiao, Xiaowei Chen, Xiaomin Chen, Dongdong Zhang, Rui Xing, Xin Tong, Nan Wu, Jian Zhao, Youyong Lu, Mingzhou Guo, Runsheng Chen. Transcriptional profiling analysis and function
2. Tengfei Xiao#, Lihui Liu#, Hongling Li#, Yu Sun#, Huaxia Luo, Tangping Li, Shihua Wang, Stephen Dalton, Robert Chunhua Zhao, Runsheng Chen. Long Noncoding RNA ADINR Regulates Adipogenesis by Transcriptionally Activating C/EBPα. Stem Cell Reports. 2015; 5: 856-865. (Co-first author)
3. Jiahui Chen，Lihui Liu，Guifeng Wei，Wei Wu，Huaxia Luo，JiaoYuan，Jianjun Luo，Runsheng Chen. The long noncoding RNA ASNR regulates， degradation of Bcl-2 mRNA through its interaction with AUF1. Sci Rep-Uk. 2016; 6: 32189
4. Guifeng Wei, Huaxia Luo , Yu Sun, Jiagen Li, Liqing Tian, Wei Liu, Lihui Liu, Jianjun Luo, Jie He, Runsheng Chen. Transcriptome profiling of esophageal squamous cell carcinoma reveals a long noncoding RNA acting as a tumor suppressor. Oncotarget. 2015; 6: 17065-17080.
5. Tengfei Xiao, Yunfei Wang, Huaxia Luo, Lihui Liu, Guifeng Wei, Xiaowei Chen, Yu Sun, Xiaomin Chen, Geir Skogerbø, Runsheng Chen. A differential sequencing-based analysis of the C. elegans noncoding transcriptome. Rna-a Publication of the Rna Society. 2012; 18: 626-639.
6. Jiao Yuan, Haiyan Yue, Meiying Zhang, Jianjun Luo, Lihui Liu, Wei Wu, Tengfei Xiao, Xiaowei Chen, Xiaomin Chen, Dongdong Zhang, Rui Xing, Xin Tong, Nan Wu, Jian Zhao, Youyong Lu, Mingzhou Guo, Runsheng Chen. Transcriptional profiling analysis and function